You can use them, but you do give up one of the absolute least-expensive ways to make power. First off, unless you have $2000 worth of hand porting done on the heads, they're not going to flow like a good out-of-the-box aluminum head. Second, the intake/exhaust flow ratios are not as ideal as many aluminum heads when used in blowe applications- you need alot of exhaust flow relative to the intake. lastly, the inherent thermal abilities of the aluminum allow you to get away with a bit more boost and a bit more timing. You could see 100 to 150 hp on a mildly blown 540 simply by bolting on a set of heads. AFR 315CNC's are about $3 grand. Where else can you find 150 hp for that kind of money?